The HACS (Hydrodynamic-Actualized Cell Sorter) is a general-purpose automated microfluidic sorting platform targeted at both basic life science research and clinical translational applications. The system exhibits broad compatibility with multiple sample types, including single cells, multicellular aggregates, organoids, and microspheres.
The integration of reusable microfluidic module lowers costs and eliminates disposable chip batch variability. With customizable parameters and fully automated process, it reduces human error and improves reproducibility for high-precision clinical and research use.
Particles flowing through a microspiral channel experience two additional size-dependent forces: Dean drag and inertial lift. An inner-shallow, outer-deep channel design creates a bistable state: large particles focus on the inner wall (inertial lift dominant), small particles trap on the outer wall (Dean drag dominant). This enables purely hydrodynamic sorting of suspended particle samples.
The core sorting module μFCPU (Microfluidic Cell Processing Unit) is fabricated using our proprietary LMAC process. Constructed from highly stable materials, the module contains no irreversible modifications, allowing for long-term repeated use.
